Here, we take a pictorial look back at meetings between the two sides from years gone by.
Mansfield Town made to pay for missed chances as they lose at Leyton Orient
Only finishing missing in another fine Mansfield Town display says boss Nigel Clough, but injury list lengthens for his depleted squad in Leyton Orient defeat
One more new face in for Mansfield Town as early injuries mount?
Former Mansfield Town boss Mick Jones dies aged 75
Supercomputer predicts the most likely result for Leyton Orient v Mansfield Town, Bradford City v Newport County, Stockport County v Colchester United and every other League Two game