England come into the game on a high after beating Croatia in their opening game, while the Scots suffered a disappointing loss to the Czechs in their opener.
England are favourites but, as we all know in football, the formbook goes out of the window in derby games.
Here, we look back at nine famous meetings between the old enemies.
9. Scotland 2 England 2, June 10, 2018
The most recent meeting between the two was in qualifying for the last World Cup and, just like the first ever game, Scotland were seconds away from a famous win. Harry Kane rescued a draw for England. Photo: Mike Hewitt/Getty images
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